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How effective is Proscar 5mg?
Proscar is a drug with an antiandrogenic effect. Proscar is prescribed in the treatment of benign prostatic hyperplasia (BPH) to prevent the development of urological complications reducing the need for surgery, improving urine flow, reducing the size of the enlarged prostate and the severity of the disease-related symptoms. The drug is indicated for men with an enlarged prostate gland.
Composition of Proscar drug
The tablets covered with a cover of blue color having the shape of an apple, with the engraving “MSD 72” on one side and “PROSCAR” on the other side. 1 tab is Finasteride 5 mg.
Excipients: lactose monohydrate, pregelatinized starch (corn), sodium carboxymethyl ether starch, iron oxide yellow, sodium docusate, microcrystalline cellulose, magnesium stearate.
Composition of the film sheath: methylhydroxypropylcellulose, hydroxypropyl cellulose, titanium dioxide, talc, indigo carmine aluminum varnish.
When are you recommended to use Proscar 5mg?
This drug is recommended for use in the manifestation of benign prostatic hyperplasia. This disease can manifest itself in the form of a decrease in the maximum rate of urinary outflow, with the risk of acute urinary retention due to poor permeability of the urinary canals. When treating these ailments, Proscar has the best reviews both from patients and from specialists.
Pharmachologic action of Proscar
Being an antitumor hormone drug, Proscar inhibits 5-alpha-reductase, which converts testosterone into the more active 5-alpha dihydrotestosterone. It also reduces its concentration in blood and prostate tissue within 24 hours after oral administration.
It oppresses the stimulating effect of testosterone on the development of the tumor. Suppression of the formation of dihydrotestosterone is accompanied by a decrease in the volume of the prostate gland, an increase in the maximum urinary flow rate and a decrease in symptoms of obstruction of the urinary tract. With constant admission, a statistically significant effect is recorded after 3 months (decrease in the volume of the gland), 4 months (increase in the maximum urinary flow rate) and 7 months (decrease in the general symptoms and symptoms of obstruction of the urinary tract).
How to use Proscar 5mg?
Proscar is taken orally, regardless of food intake, either as monotherapy or concomitantly with doxazosin. The daily dose is 1 tablet (5 mg). Patients with renal failure of varying severity as well as elderly patients don’t require individual dose adjustment.
Are you contraindicated to use Proscar?
- Hypersensitivity to the components of the drug.
- Proscar is not indicated for use in women and children.
With caution the drug should be used by patients with a large volume of residual urine and / or significantly reduced urine flow (as in this case careful monitoring for obstructive uropathy should take place).
Which side effects are possible?
Possible side effects:
- Endocrine system: tenderness and enlargement of the mammary glands;
- Sexual system: decrease in ejaculate volume, decreased libido, impotence, tenderness of the testicles, ejaculation disorders;
- Allergic reactions: rash, hives, itching, angioedema, edema of the face and lips.
The duration of therapy has no effect for the frequency of development and the severity of the disturbances. The number of cases of sexual function violations associated with the reception of Proscar decreases with the prolonged admission of the drug. Avoid side effects and achieve maximum effectiveness in drug treatment, it is necessary to strictly adhere to the dosage and course of treatment prescribed by the treating specialist.
There was no clinically significant interaction between Proscar and other drugs.
Apparently, Proscar does not exert a noticeable effect on the activity of cytochrome P450 isoenzymes and on the pharmacokinetics of drugs in which these isoenzymes participate in the metabolism. There were no clinically significant manifestations of drug interaction with the combined use of Proscar with the following drugs: propranolol, digoxin, glyburide, warfarin, theophylline, ACE inhibitors, acetaminophen, acetylsalicylic acid, alpha-adrenoblockers, beta adrenoblockers, calcium channel blockers, nitrates, diuretics, histamine H2 receptor blockers, HMG-CoA inhibitors Reductase, NSAIDs, quinolones and benzodiazepines.
In patients with a large volume of residual urine and / or a sharply reduced urine flow, careful monitoring of the possible development of obstructive uropathy when taking Proscar should be performed.
Before the beginning of Proscar therapy, it is necessary to exclude diseases that simulate benign prostatic hyperplasia. They are the following: prostate cancer, urethral stricture, bladder hypotension, disturbances in its innervation and infectious prostatitis.
Women of childbearing age and pregnant women should avoid any contacts with the drug due to the fact that it has teratogenic properties. The ability to suppress the conversion of testosterone to dihydrotestosterone can cause impaired development of the genital organs in the male fetus. It also penetrates into the seminal fluid.
It causes a decrease in prostate-specific antigen at 6 and 12 months of admission by 41 and 48%, respectively. To exclude the development of prostate cancer during the treatment with Proscar, patients should be examined.
How to buy Proscar 5mg online?
Proscar is a very well-known drug available atany online pharmacy. To buy this drug online is the most convenient way as you can use an online order form offered at the website.The operator will answer all your questions. Pharmacies online can guarantee you the reasonable price and professional consultation of the specialists. No need to have doubts concerning the quality of the drug as all deliveries of drugs are performed only from manufacturing plants that have already proved their high-quality standards around the world.